When working with midpoints, I never liked to have to create a point at middle of a line/ curve in order to add relationship or perform any action to other entities.
Also, you could only select midpoints of model edges while dimensioning using Select Midpoint from shortcut menu. However, on selection of a second midpoint on another entity, the first entity was cleared.
In SW2016, you can dynamically highlight and select midpoints directly on sketch entities and model edges while in sketch mode for adding relations. You can also dynamically highlight and select midpoints of sketch entities while using dimensions in sketches.
Dynamic highlight to midpoint of a sketch entity
Dynamic highlight to midpoint of a model edge
Simple things like this just makes my life so MUCH easier :P
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Senior Data Management Engineer | CSWP-D